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Education

Swansea Uni to deliver advanced therapies

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A significant opportunity: University a centre for cell and gene therapies

SWANSEA U​NIVERSITY’S​ Medical School, through its partnership with Abertawe Bro Morgannwg University Health Board, is to be one of the centres to deliver advanced medical therapies to Wales, which is part of a major investment announced by Welsh Blood Services.

A recently formed health consortium, jointly led by the Welsh Blood Service (on behalf of NHS Wales) and the National Institute for Health Research Birmingham Biomedical Research Centre, has been awarded £7.3M of UK Government funding to ensure more patients benefit from a new generation of breakthrough therapies.

£1.5M will come directly to NHS Wales and £550K to Trakcel, a Welsh software company developing scheduling/tracking software for advanced therapies which is based upon technology developed at Swansea University.

The funding will support the Welsh Government’s commitment to developing an Advanced Therapies Strategy which will enable these therapies to be brought to Welsh patients and Advanced Therapy Medicinal Product (ATMP) companies to reach the clinical market, whilst building expertise, capability and capacity across NHS Wales to benefit patient outcomes.

Speaking of the award, Frank Atherton, Chief Medical Officer for Wales, said: “We welcome the announcement of the successful partnership between Birmingham, Nottingham and Wales NHS centres in bidding for Innovate UK monies. The project is aligned with our ambition to support the development, availability and adoption of new innovative therapies for patients in Wales. Cell- and gene-based advanced therapies offer exciting opportunities, not only for the way we treat people with previously incurable conditions, but also how we work together with industry and NHS Wales in bringing these treatments from bench to bedside.”

The NHS Wales role in the MW-ATTC consortium was led by the Welsh Blood Service, with support from Abertawe Bro Morgannwg and Cardiff & Vale University Health Boards along with the Life Sciences Hub Wales Special Interest Group on Cell and Gene Therapy, which brings together expertise from the Welsh NHS, Universities and industry in the Life Science sector.

As part of the contract award, one of the first advanced therapy treatment sites in Wales will be established within Abertawe Bro Morgannwg at the Joint Clinical Research Facility (JCRF) at Swansea University’s Medical School. The focus of the centre will be to develop the infrastructure, processes and skilled workforce required to enable patients to be cared for, from diagnosis through to post-treatment follow up.

Cath O’Brien, Director of the Welsh Blood Service and MW-ATTC Co-Director, said: “A significant opportunity exists to position Wales as a leader in clinical trial and routine delivery of cell and gene therapies to maximise Welsh patient benefit and opportunities for the national economy. The Welsh Government is committed to exploring these revolutionary developments in healthcare and we are excited to have worked alongside our consortium partners to secure funding through what was a highly competitive tendering process.”

One of the first products that will pass through the Welsh centres is that being developed by one of the consortium partners, Rexgenero and is intended to prevent the need for diabetes-related lower limb amputations for some no option patients. The incidence of diabetes is continuing to increase in Wales and already accounts for ~10% of the NHS Wales budget (£500M) with 200, 000 sufferers today rising to an estimated 500,000 by 2025. Currently around 2000 patients in Wales have non-healing lower limb ulcers that result in approximately 330 amputations per year.

The Midlands & Wales Advanced Therapy Treatment Centre (MW-ATTC) will identify barriers, challenges and solutions to facilitate future deployment and adoption of these transformative therapies within the UK healthcare system.

Advanced treatments, such as cell and gene therapies, show great promise for patients with chronic and terminal conditions that currently cannot be cured. Unlike conventional medicines, these new approaches often aim to selectively remove, repair, replace, regenerate and re-engineer a patient’s own genes, cells and tissues to restore normal function. The project will include potential treatments for arthritis, liver disease, several types of cancer, and diabetic ulcers.

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Community

Staff experience what dementia may feel like

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During Autumn 2019 Ceredigion County Council staff and elected members were given the opportunity to take part in a Virtual Dementia Tour (VDT). By using specialist equipment and creating a simulated environment, the experience gave an insight into what dementia might feel like.

Donna Pritchard, Corporate Lead Officer Porth Ceredigion and Deputy Statutory Director for Social Services said: “This has been a very thought-provoking experience. It’s allowed participants to physically and emotionally feel what it would be like to live with Dementia and to acknowledge the challenges to overcome that sensory loss brings.”

Dementia is a syndrome (a group of related symptoms) associated with an ongoing decline of brain functioning. This may include problems with memory loss, thinking speed, mental sharpness and quickness, language, understanding judgement, mood, movement and difficulties carrying out daily activities.

Donna continued: “The Virtual Dementia Tour identifies ways to improve communication for people living with dementia and ways that care and support staff can change their practice to improve their lives and help them achieve positive outcomes. All our staff at residential homes have been trained to ensure that people with dementia are supported in an inclusive environment.”

Staff yn cael profiad o’r hyn y gall dementia deimlo fel

Yn ystod yr Hydref 2019 rhoddwyd cyfle i staff ac aelodau etholedig Cyngor Sir Ceredigion gymryd rhan mewn ‘Virtual Dementia Tour‘ (VDT). Drwy ddefnyddio offer arbenigol a chreu amgylchedd ffug, roedd y profiad yn rhoi cipolwg ar yr hyn y gallai dementia ei deimlo.

Dywedodd Donna Pritchard, Swyddog Arweiniol Corfforaethol Porth Ceredigion a Dirprwy Gyfarwyddwr Statudol Gwasanaethau Cymdeithasol: “Mae hwn wedi bod yn brofiad sy’n ysgogi’r meddwl. Mae’n caniatáu i gyfranogwyr deimlo sut beth fyddai fyw gyda dementia, yn gorfforol ac yn emosiynol, a chydnabod yr heriau i oresgyn y golled synhwyraidd honno.”

Mae dementia yn syndrom (grŵp o symptomau cysylltiedig) sy’n gysylltiedig â dirywiad parhaus o ran gweithrediad yr ymennydd. Gall hyn gynnwys problemau o ran colli cof, cyflymder meddwl, miniogrwydd meddwl a chyflymdra, iaith, deall dyfarniad, hwyliau, symud ac anawsterau’n cyflawni gweithgareddau dyddiol.

Parhaodd Donna: “Mae’r ‘Virtual Dementia Tour’ yn nodi ffyrdd o wella’r cyfathrebu ar gyfer pobl sy’n byw gyda dementia a ffyrdd y gall staff gofal a chymorth newid eu hymarfer i wella eu bywydau a’u helpu i gyflawni canlyniadau cadarnhaol. Mae pob un o’n staff mewn cartrefi preswyl wedi cael eu hyfforddi i sicrhau bod pobl â dementia yn cael eu cefnogi mewn amgylchedd cynhwysol.”

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Education

Seren and Sbarc kick off new series of books with a story to coincide with Rugby World Cup

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WELSH Government and WRU announced a partnership to encourage more school children to use Welsh.

They have been inspiring school children to use Welsh in and out of the classroom for a while, but Siarter Iaith mascots Seren a Sbarc have now moved on to the next level with their very own book. Released as part of a partnership, the book will be issued to all primary schools in Wales to encourage children to read more Welsh and to cheer Wales on in Welsh.

The book, Seren a Sbarc yn Achub (Cwpan) y Bydysawd (Seren a Sbarc Save the Universe (Cup)), written by Elidir Jones and illustrated by Huw Aaron, tells the tale of the heroic characters fighting off monsters and villains using the skills they have learnt through rugby and speaking Welsh.

The book gives children and parents fun way of learning and using Welsh through rugby, as the nation eagerly watches Wales on their World Cup journey.

All primary schools in Wales will receive copies of the book to help inspire the next generation of Welsh speakers as part of the Siarter Iaith.

Minister for International Relations and Welsh Language, Eluned Morgan, said: “As rugby fever grips the country, children right across Wales will be reading about the heroic antics of Seren and Sbarc as they fight off monsters with their fantastic Welsh and sport skills! This exciting project with the WRU is a great way of inspiring the next generation of Welsh speakers, and future rugby players. Rugby is a sport that brings the nation together and the Welsh language is a big part of that.”

To launch the book, Seren and Sbarc joined pupils of Ysgol Bro Allta in Ystrad Mynach for a busy day of rugby practice and sending good luck messages to the Wales team. Dragons players Aaron Jarvis and James Benjamin also joined the Year 5 and 6 pupils as they carried out tasks from the WRU Digital Classroom resource, launched to inspire pupils to achieve in all areas through rugby.

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Education

Ceredigion Schools Succeed in Exam Results

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The GCSE exam results published today (22 August) by the WJEC show that very high standards are being maintained in Ceredigion schools.

 

98.8% of entries for WJEC exams were graded A* to G, with 24.9% of the entries achieving A* and A grades. 72.5% of entries were graded A* to C.

 

Councillor Catrin Miles is the Cabinet member responsible for Learning Services. She said, “We are delighted with Ceredigion pupils’ achievements in a wide range of subjects. They have proven once again that hard work and commitment leads to success. I would like to sincerely thank staff and governors for their leadership and their continued support for our pupils. We wish the young people of Ceredigion the very best as they confidently progress on their chosen path.”

 

The following table provides the figures for Ceredigion and Wales:

           Ceredigion                                                Wales
Grade   A* – A                              24.9%                                                     18.4%
Grade A*-C                                  72.5%                                                     62.8%
Grade A*-G                                 98.8%                                                     97.2%

 

Compared with the Welsh average, an additional 6% of Ceredigion entries achieved A*-A grades and, in the case of A*-C grades, Ceredigion’s entries achieved almost 10% more than the Welsh average.

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