Narberth win nail bitter
THE OTTERS snatched a bonus point victory from the jaws of defeat in the dying moments of their tough game away to Blackwood.
Narberth were behind for large periods of the game, trailing 16-13 at half time. Blackwood scored 13 early unanswered points as Narberth took their time to settle into the fixture.
The Otters scored their first half points in the last 20 minutes of the half, as fly half Ianto Griffiths landed a penalty, and converted Morgan Griffiths’ try, before specialist long-distance kicker Nick Gale stepped up to the kicking tee, and struck a cracking long-range penalty.
The second half began much like the first, with the Otters on the back foot and Blackwood extending their lead to 28-13. If the first 20 minutes of the half belonged to Blackwood, then the final quarter of the game belonged entirely to Narberth, as they upped their intensity and stringed together some beautiful phases to crawl back into a strong position.
Steffan Phillips got the visitors rolling with a well taken try, as the number 8 went on a typical bull-dozering run to touch down, with Ianto Griffiths adding the conversion. Griffiths would then find a space in midfield and used his feet to sneak through the tiring Blackwood defence to score a try of his own.
As the travelling supporters found their voice in dying moments, Narberth dug deep, as the forwards slowly moved their way upfield, before the hero of the day second-row Alex Jenkins, found himself with the ball and crossed the whitewash to record a memorable victory for Narberth.
Crymych’s second half slip up
CRYMYCH conceeded an 11-point lead to slip to a two point defeat at home to Cwmllynfell due to ill-discipline in the second half.
The first 40 minutes of play belong to the Preseli Men as scrum-half Rhys Davies, back from a stint with Premiership side Llanelli, slotted two penalties before Guto Griffiths continued his try scoring form, touching down in the corner. Griffiths had crossed in the corner earlier, but the try had been disallowed, much to the frustration of the home crowd.
Leading 11-0 at half time, Crymych were looking good for the victory, but so much can happen in 40 minutes of play.
Dyfan Dafydd added an extra penalty for Crymych, however Cwmllynfell dug their heels in and began to muscle their way back into the game. Craig Kelly, Daniel Jones and Luke Battenbow all scored for the visitors.
Crymych did manage a try through Gavin Thomas, but some ill-discipline in the final moments of the game, gifted Cwmllynfell two kickable penalties, which Tristan Lewis happily obliged to convert to give his team an unlikely victory, and leave the Crymych faithful frustrated.
Whitland wither at home
LEAGUE LEADERS Waunarlwydd were too strong in the second half for the Borderers, as they only trailed by four points at the break.
Aidan Laxton scored Whitland’s only first half try and Nico Setaro struck two penalties. Waunarlwydd secured the bonus point victory in the second half with some outstanding play from the whole 15 players, before Whitland scored a consolation try through Laxton, and Setaro struck his third penalty.
First win for Blues
HAVERFORDWEST finally got their season on track with a hard fought home victory against a difficult Tumble side.
The Blues started the game with great intent as Ryan Banner and Scott Candler crossed the white-wash, as full back Ashley Sutton converted both.
However, these were the only points of the game for Haverfordwest, as they lost their discipline, and Tumble’s Steve Hewitt slotted three penalties for his side. The height of frustration for the Blues came when both Sutton and Adam Williams were sin-binned, but stern defensive work meant their try line remained intact.
Haverfordwest’s Ashley Sutton said after the game: ‘’It was really important to get the first win on Saturday. The boys have worked really hard in pre-season and deserved a few wins in previous weeks, but hopefully now the win on Saturday will kick start their season.’’
Tenby remain undefeated
Tenby United 12
TENBY remain at the top of their division after a hard fought match away to Cardigan.
The drama began in the first half as Cardigan’s Emyr Harries was red-carded, and Tenby scored their opening try through Jack Guerriro, converted by Jonathan Rodgers. The Cardi’s then replied with Dorian Butler touching down, with Iestyn Crompton adding the extras.
The second half was a war of attrition as only Tenby’s Dai Meyrick was able to cross the try line, maintaining Tenby’s unbeaten record.
Miserable day for Milford
Milford Haven 0
MILFORD HAVEN’s season continued down a bad path as they remained scoreless away from home, conceding no fewer than 50 points.
Effort was seen from all Milford players, but a lack of confidence from this season’s results cumulated in another poor performance for the Mariners.
Fishguard fall short
Fishguard & Goodwick 21
THE SEAGULLS fell short in the final moments of play as Laugharne were able to take the lead, and the victory through a converted try.
Simon James again led from the front for Fishguard as he touched down twice, along with centre Mike Jenkins, with scrum half Alun George adding two penalties to the total.
But some missed opportunities to see the game off from Fishguard allowed Laugharne to snatch victory from the Seagulls.
Quins win hard derby
Pembroke Dock Harlequins 17
THE QUINS secured their first win of the season with typically brutal contest against Neyland in an entertaining game.
Neyland’s Delme Bateman opened the day’s scoring with a try in the corner, before Gregg Miller slid over for a try. The Quins battled back through Alex Pearce, converted by Adam Cawley. Arian Heath was then able to cross for the Quins, again converted by Cawley.
A final Cawley penalty secured the victory for the Quins, with Neyland picking up a losing bonus point.
Scarlets lose 100% record
PEMBROKE lost their first game of the season, as both sides entered this contest undefeated.
In a tight game, neither side gave an inch, but it was the Pontyates kicker who edged his team ahead, as he maintained pressure on the Scarlets.
Lewis Davies scored Pembroke’s only points with a well struck penalty, but it wasn’t enough as Pontyates prevailed.
Wasps stung away from home
St Clears 41
LLANGWM were only able to manage three points away from home as they met a strong St Clears side.
Andrew Brock kicked the three-pointer for the Wasps, but an impressive individual haul of 21 points for St Clears’ Chris Rodenhurst helped his side claim a bonus point victory.
Saints well beaten on the road
Burry Port 80
St Davids 5
TRAVELLING with the bare minimum 15 players, St Davids were always up against it as they faced the promotion favourites Burry Port on their home patch.
Trailing 46-0 at half time, the Saints would be forgiven for imploding, but they refused to lay down, and in the second half, mustered the power to work up-field, with Russell Watkins scoring for the Saints.
Police trying to track stolen tanker
DYFED-POWYS POLICE is investigating the theft of a fuel tanker containing approximately 8,500 litres of diesel (4,000 litres of red diesel and 4,500 litres of white diesel).
The vehicle was taken from Tan Y Foel Quarry, Cefn Coch, Welshpool, between 5.30pm on Wednesday, May 23 and 6am on Thursday, May 24.
The police are asking people to see if the tanker is now in this area.
Anyone with information that can help officers with their investigation is asked to report it by calling 101. If you are deaf, hard of hearing or speech impaired text the non-emergency number on 07811 311 908, quoting Ref: DPP/0006/24/05/2018/01/C.
Reprogrammed virus offers hope as cancer treatment
A CANCER treatment that can completely destroy cancer cells without affecting healthy cells could soon be a possibility, thanks to research led by Cardiff University.
The team of researchers has successfully ‘trained’ a respiratory virus to recognise ovarian cancer and completely destroy it without infecting other cells. The reprogrammed virus could also be used to treat other cancers such as breast, pancreatic, lung and oral.
Dr Alan Parker from Cardiff University’s School of Medicine said: “Reprogrammed viruses are already being used in gene therapy procedures to treat a range of diseases, demonstrating they can be trained from being life-threatening into potentially lifesaving agents.
“In cancer treatment, up until now, reprogrammed viruses have not been able to selectively recognise only the cancer cells and would also infect healthy cells, resulting in unwanted side effects.
“We’ve taken a common, well-studied virus and completely redesigned it so that it can no longer attach to non-cancerous cells but instead seeks out a specific marker protein called αvβ6 integrin, which is unique to certain cancer cells, allowing it to invade them.
“In this case we introduced the reprogrammed virus to ovarian cancer which it successfully identified and destroyed.
“This is an exciting advance, offering real potential for patients with a variety of cancers.”
Once the virus enters the cancer cell it uses the cell’s machinery to replicate, producing many thousands of copies of itself, prior to bursting the cell and thereby destroying it in the process. The newly released viral copies can then bind and infect neighbouring cancer cells and repeat the same cycle, eventually removing the tumour mass altogether.
The virus also activates the body’s natural immune system, helping it to recognise and destroy the malignant cells.
The reprogrammed virus is from a group of respiratory viruses called adenoviruses. The advantage of using these viruses is that they are relatively easy to manipulate and have already been safely used in cancer treatment.
The technique used to reprogramme the virus to identify the protein common to ovarian, breast, pancreatic, lung and oral cancers could also be used to manipulate it so that it would recognise proteins common to other groups of cancers.
Additional refinement to the viral DNA could also allow the virus to produce anticancer drugs, such as antibodies, during the process of infecting cancer cells. This effectively turns the cancer into a factory producing drugs that will cause its own destruction.
The research was carried out in a laboratory, using mice with ovarian cancer, and has not yet reached clinical trials. The next step is to test the technique with other cancers, with a view to starting clinical trials in five years’ time.
Dr Catherine Pickworth from Cancer Research UK said: “It’s encouraging to see that this virus, which has been modified to recognise markers on cancer cells, has the ability to infect and kill ovarian cancer cells in the lab. Viruses are nature’s nanotechnology and harnessing their ability to hijack cells is an area of growing interest in cancer research.
“The next step will be more research to see if this could be a safe and effective strategy to use in people.”
The team includes researchers from Cardiff University; the Mayo Clinic in Rochester, USA; Glasgow University; the South West Wales Cancer Institute; and Velindre Cancer Centre.
The research was funded by Cancer Research UK, Tenovus Cancer Care and Cancer Research Wales.
The paper ‘Ad5NULL-A20 – a tropism-modified, αvβ6 integrin-selective oncolytic adenovirus for epithelial ovarian cancer therapies’ is published in Clinical Cancer Research.
Money raised by Canolfan Padarn in the Race for Life
STAFF and service users from Canolfan Padarn took part in this year’s Race for Life which took place on Sunday, May 13.
Service users Debbie, Lowri and Donna had been training for months as part of the centre’s healthy lifestyle group and were joined by staff members Lina, Ellie-May, Heather, Jenny, Dawn and Anwen, along with Heather’s daughter Cala, and Anwen’s daughter Jena.
Canolfan Padarn Support Worker Ellie-May Watkins said: “The crowd gave the crew great support and we’re grateful to everyone who cheered us on. We’d like to say a huge thank you to Queens Road Bowling Club for use of their facilities on the day. Previously, Canolfan Padarn raised £330 for Cancer research, we hope that we will match or exceed that in sponsorship this year.”
Canolfan Padarn is a community resource base for adults with learning disabilities in Aberystwyth, offering social, leisure and work opportunities in the local area.
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