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Swansea Uni to deliver advanced therapies

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A significant opportunity: University a centre for cell and gene therapies

SWANSEA U​NIVERSITY’S​ Medical School, through its partnership with Abertawe Bro Morgannwg University Health Board, is to be one of the centres to deliver advanced medical therapies to Wales, which is part of a major investment announced by Welsh Blood Services.

A recently formed health consortium, jointly led by the Welsh Blood Service (on behalf of NHS Wales) and the National Institute for Health Research Birmingham Biomedical Research Centre, has been awarded £7.3M of UK Government funding to ensure more patients benefit from a new generation of breakthrough therapies.

£1.5M will come directly to NHS Wales and £550K to Trakcel, a Welsh software company developing scheduling/tracking software for advanced therapies which is based upon technology developed at Swansea University.

The funding will support the Welsh Government’s commitment to developing an Advanced Therapies Strategy which will enable these therapies to be brought to Welsh patients and Advanced Therapy Medicinal Product (ATMP) companies to reach the clinical market, whilst building expertise, capability and capacity across NHS Wales to benefit patient outcomes.

Speaking of the award, Frank Atherton, Chief Medical Officer for Wales, said: “We welcome the announcement of the successful partnership between Birmingham, Nottingham and Wales NHS centres in bidding for Innovate UK monies. The project is aligned with our ambition to support the development, availability and adoption of new innovative therapies for patients in Wales. Cell- and gene-based advanced therapies offer exciting opportunities, not only for the way we treat people with previously incurable conditions, but also how we work together with industry and NHS Wales in bringing these treatments from bench to bedside.”

The NHS Wales role in the MW-ATTC consortium was led by the Welsh Blood Service, with support from Abertawe Bro Morgannwg and Cardiff & Vale University Health Boards along with the Life Sciences Hub Wales Special Interest Group on Cell and Gene Therapy, which brings together expertise from the Welsh NHS, Universities and industry in the Life Science sector.

As part of the contract award, one of the first advanced therapy treatment sites in Wales will be established within Abertawe Bro Morgannwg at the Joint Clinical Research Facility (JCRF) at Swansea University’s Medical School. The focus of the centre will be to develop the infrastructure, processes and skilled workforce required to enable patients to be cared for, from diagnosis through to post-treatment follow up.

Cath O’Brien, Director of the Welsh Blood Service and MW-ATTC Co-Director, said: “A significant opportunity exists to position Wales as a leader in clinical trial and routine delivery of cell and gene therapies to maximise Welsh patient benefit and opportunities for the national economy. The Welsh Government is committed to exploring these revolutionary developments in healthcare and we are excited to have worked alongside our consortium partners to secure funding through what was a highly competitive tendering process.”

One of the first products that will pass through the Welsh centres is that being developed by one of the consortium partners, Rexgenero and is intended to prevent the need for diabetes-related lower limb amputations for some no option patients. The incidence of diabetes is continuing to increase in Wales and already accounts for ~10% of the NHS Wales budget (£500M) with 200, 000 sufferers today rising to an estimated 500,000 by 2025. Currently around 2000 patients in Wales have non-healing lower limb ulcers that result in approximately 330 amputations per year.

The Midlands & Wales Advanced Therapy Treatment Centre (MW-ATTC) will identify barriers, challenges and solutions to facilitate future deployment and adoption of these transformative therapies within the UK healthcare system.

Advanced treatments, such as cell and gene therapies, show great promise for patients with chronic and terminal conditions that currently cannot be cured. Unlike conventional medicines, these new approaches often aim to selectively remove, repair, replace, regenerate and re-engineer a patient’s own genes, cells and tissues to restore normal function. The project will include potential treatments for arthritis, liver disease, several types of cancer, and diabetic ulcers.

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Education

Ceredigion Schools have already produced more than 300 visors

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MORE than 300 face-visors have already been produced by staff at Ysgol Bro Pedr, Ysgol Penglais, Ysgol Bro Teifi and Ysgol Uwchradd Aberteifi.

These face-visors provide much needed protection for front-line workers in Ceredigion. The visors are produced on the schools’ 3-D printers.
Plans are in place to produce another 2,000 of these vital visors.

Meinir Ebbsworth, Corporate Lead Officer – Schools said, “We are extremely grateful to our staff who are using their expertise and school equipment to help others.”

Ceredigion County Council are proud of the contribution that our schools are making during this difficult and challenging times, and to all our staff and volunteers who have shown such goodwill to help others.

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Education

Ceredigion pupils receive Holocaust survivor experiences

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To mark Holocaust Memorial Day, Ceredigion pupils had the opportunity to hear the story of a Holocaust survivor.

On 27 January 2020, it was the 75th anniversary of the liberation of the Nazi concentration and death camp Auschwitz-Birkenau. Dr Martin Stern MBE was five years old when he was arrested at his school.

His journey was a difficult one being close to death on a few occasions. Dr Stern moved to Britain in 1950 and became a Doctor. These days, Dr Stern is educating young people about what happened. On 29 January 2020, he came to Aberaeron to talk to a hall full of Ceredigion’s young people.

Meinir Ebbsworth, Corporate Lead Officer for Schools said, “75 years ago, the world saw images of people coming out of the camps and coming to terms with what had happened. We are so grateful to Dr Martin Stern for coming to Ceredigion to share his story and experiences. It is not easy to talk about a very dark time in the world’s history. I hope our pupils have considered what we had heard. Due to the overwhelming silence in the room when Dr Stern was speaking, I think they really appreciated the afternoon.”

The afternoon was jointly organised by Ceredigion County Council’s schools service and ERW.

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Education

Bronze-medal winning hairdresser on the road to Shanghai

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Hyfforddiant Ceredigion Training (HCT) continue to lead the way in skills competitions across the UK. The latest success story is Bayley Harris, who recently qualified as a Level 2 hairdresser at HCT.

After succeeding in demanding regional and national qualifying rounds, Bayley earned a spot in the grand final of the WorldSkills UK competition which was held from 21 to 23 November 2019 at the NEC in Birmingham.

The competition took place over three full days, with Bayley having to compete in five different categories including dressing long hair, cutting, colouring, bridal hair and barbering. She finished in third place out of a total of ten top-class hairdressers, earning her the bronze medal in the awards ceremony.

As a result of her outstanding performance, Bayley has been selected for the Squad UK for the prestigious international WorldSkills Competition which will take place in Shanghai, China in 2021.

HCT hairdressing tutor Carys Randell, congratulated Bayley for doing so well in the competitions, as they were very intense and of an extremely high standard. She went on to add, “I am so proud of Bayley for coming third in the UK, and I look forward to supporting her on her next journey in Squad UK.”

The WorldSkills competition in Shanghai will feature over 1000 of the world’s most talented apprentices and students competing in over 50 different skills as they battle it out to be named the World Champion in their respective vocation.

Catrin Miles is the Cabinet member responsible for Learning Services and Life-long learning. She said, “It’s great to follow Bayley’s journey within the hairdressing industry. This latest award is a credit to her. Bayley shows where you can reach if you put your mind to work with the support of Ceredigion Training. Good luck in the UK Squad.”

All staff and learners at HCT would like to congratulate Bayley in her most recent competition success and wish her all the best in her bid to represent the UK in China in 2021.

Hyfforddiant Ceredigion Training (HCT) offers a range of vocational courses for people of all ages, including Hairdressing, Childcare, Business Administration, Information Technology, Carpentry, Plumbing, Electrics, Blacksmithing, Motor Mechanics, and Welding. For more information, find HCT on Facebook: https://www.facebook.com/HyfforddiantCeredigion, or visit the website: http://www.ceredigiontraining.co.uk/hafan.

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